The nonprofit eLife receives funding from the Howard Hughes Medical Institute, which also supports The Associated Press Health and Science Department.Īmong the studies that did not hold up was one that found a certain gut bacteria was tied to colon cancer in humans. Overall, 54% of the original findings failed to measure up to statistical criteria set ahead of time by the Reproducibility Project, according to the team's study published online Tuesday by eLife.
By the time cancer drugs reach the market, they’ve been tested rigorously in large numbers of people to make sure they are safe and they work.įor the project, the researchers tried to repeat experiments from cancer biology papers published from 2010 to 2012 in major journals such as Cell, Science and Nature. The new study reflects on shortcomings early in the scientific process, not with established treatments. “Progress in cancer is always slower than we hope.” Researchers lose prestige if their results don’t hold up to scrutiny, she said.Īnd there are built-in rewards for publishing discoveries.īut for cancer patients, it can raise false hopes to read headlines of a mouse study that seems to promise a cure “just around the corner,” Prasad said. In reality, there’s little incentive for researchers to share methods and data so others can verify the work, said Marcia McNutt, president of the National Academy of Sciences.
(National Institute of Health via AP) AP Show More Show Less 7, 2021: About half the scientific claims didn’t hold up. They recreated 50 experiments, the type of work with mice and test tubes that sets the stage for new cancer drugs. Eight years ago, a team of researchers launched a project to carefully repeat influential lab experiments in cancer research. BUKATY/AP Show More Show Less 2 of5 This image provided by the National Institutes of Health shows an osteosarcoma cell with DNA in blue, energy factories (mitochondria) in yellow and actin filaments, part of the cellular skeleton, in purple.
The lab ships more than two million mice a year to qualified researchers. 1 of5 FILE - A technician holds a laboratory mouse at the Jackson Laboratory, Jan.
0 kommentar(er)
